SCHEMBL7848795

SCHEMBL7848795

C1CCCCCC2CCCC(CCCCC1)N2

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
CHRNB2 P17787 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNA4 P43681 2/20 0.32
CHRNB3 Q05901 2/20 0.32
CHRNA6 Q15825 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL551635 1.00 CYP2C9 (0.37) CYP2C9TSHRCYP2C19TDP1MAPK1
SCHEMBL550147 1.00 CYP2C9 (0.37) CYP2C9TSHRCYP2C19TDP1MAPK1
SCHEMBL550510 0.96 CYP2C9 (0.39) CYP2C9TSHRCYP2C19TDP1MAPK1
SCHEMBL21965258 0.96 MAPK1 (0.38) CYP2C9TSHRCYP2C19TDP1MAPK1
Hydrochloric Acid SCHEMBL1819609 0.92 CYP2C9 (0.37) CYP2C9TSHRCYP2C19TDP1MAPK1
SCHEMBL16878579 0.92 MAPK1 (0.36) CYP2C9TSHRCYP2C19TDP1MAPK1
SCHEMBL550429 0.92
SCHEMBL14545648 0.92
SCHEMBL9464271 0.92 ALDH1A1 (0.36) CYP2C9TSHRCYP2C19TDP1MAPK1
SCHEMBL2290579 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998043637-A9 PEROXYNITRITE DECOMPOSITION CATALYST MONSANTO CO (US) 2001-05-03 WO claimed