Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.49 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464437 | 1.00 | HDAC1 (0.55) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL16999624 | 0.88 | HDAC1 (0.66) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL16993965 | 0.88 | HDAC1 (0.66) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL9465154 | 0.84 | MEN1 (0.54) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL9465166 | 0.84 | MEN1 (0.54) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL23791189 | 0.83 | MAPT (0.59) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL29894495 | 0.83 | MAPT (0.59) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL14360532 | 0.81 | MEN1 (0.55) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL16999798 | 0.80 | HDAC1 (0.45) | HDAC1HDAC4HDAC6MEN1KMT2A | |
| SCHEMBL9465321 | 0.79 | POLB (0.62) | HDAC6MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | claimed |
| JP-5163243-A | — | — | None | — | — | JP | disclosed |
| JP-H05163243-A | DIAMIDE DERIVATIVE OF ALPHA-AMINO ACID | AGENCY OF IND SCIENCE & TECHNOL | 1993-06-29 | — | — | JP | disclosed |
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | disclosed |