Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MECP2 | P51608 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465336 | 1.00 | POLB (0.62) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL19977039 | 0.85 | KDR (0.70) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL29152858 | 0.84 | SLC40A1 (0.70) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL5053488 | 0.82 | TDP1 (0.71) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL29918706 | 0.82 | TDP1 (0.71) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL14360891 | 0.80 | TDP1 (0.63) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL28750659 | 0.80 | TDP1 (0.63) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL28750660 | 0.80 | TDP1 (0.63) | POLBTDP1MAPTTP53MEN1 | |
| SCHEMBL9464447 | 0.79 | HDAC1 (0.55) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL9464437 | 0.79 | HDAC1 (0.55) | POLBTDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | claimed |
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | disclosed |