SCHEMBL9464591

SCHEMBL9464591

NNC(=O)C(=Cc1ccccc1)NC(=O)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.75
KMT2A Q03164 2/20 0.75
MEN1 O00255 1/20 0.75
GAA P10253 4/20 0.58
LMNA P02545 2/20 0.56
CHIA Q9BZP6 1/20 0.54
ALDH1A1 P00352 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.52
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31188757 1.00 MAPT (0.75) MAPTKMT2AMEN1GAALMNA
SCHEMBL9464619 0.86 MAPT (0.59) MAPTKMT2AMEN1GAALMNA
SCHEMBL22263078 0.84 KMT2A (0.59) MAPTKMT2AMEN1GAALMNA
SCHEMBL22263074 0.84 KMT2A (0.59) MAPTKMT2AMEN1GAALMNA
SCHEMBL18292486 0.83 KMT2A (0.55) MAPTKMT2AMEN1GAALMNA
SCHEMBL4744283 0.83 KMT2A (0.55) MAPTKMT2AMEN1GAALMNA
SCHEMBL4744286 0.83 KMT2A (0.55) MAPTKMT2AMEN1GAALMNA
SCHEMBL22263060 0.83 KMT2A (0.59) MAPTKMT2AMEN1GAALMNA
SCHEMBL1942388 0.83 MAPT (0.57) MAPTKMT2AMEN1GAALMNA
SCHEMBL7112204 0.83 MAPT (0.57) MAPTKMT2AMEN1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059928-A Fluorescent probe NHO for detecting aluminum ions and preparation method and application thereof 江苏科技大学 2024-12-03 CN disclosed
US-5254548-A Treating dysfunction of cholinergic system ADIR ET COMPAGNIE (FR) 1993-10-19 US disclosed