Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 3/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752809 | 0.78 | ACHE (1.00) | ACHE | |
| SCHEMBL9464933 | 0.74 | ACHE (0.63) | ACHECYP1A2CYP2D6ACP1SMARCA2 | |
| SCHEMBL31690833 | 0.73 | HRH3 (0.56) | ACHESIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL9464597 | 0.72 | ACHE (0.59) | ACHECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9464834 | 0.72 | ACHE (0.54) | ACHESIGMAR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9464562 | 0.72 | ACHE (0.54) | ACHESIGMAR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28007048 | 0.71 | HRH3 (0.54) | ACHESIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL12691346 | 0.71 | ACHE (0.85) | ACHE | |
| SCHEMBL1753217 | 0.71 | ACHE (0.57) | ACHESIGMAR1 | |
| SCHEMBL1753197 | 0.71 | ACHE (0.57) | ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |