Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678894 | 0.86 | MEN1 (0.35) | MEN1KMT2AGAAKDM1AHTR2A | |
| Bromide SCHEMBL28573320 | 0.79 | KDM1A (0.33) | MEN1KMT2AGAAKDM1AHTR2A | |
| SCHEMBL11874756 | 0.73 | CACNB4 (0.32) | ALDH1A1 | |
| SCHEMBL12238736 | 0.73 | GPR3 (0.32) | GPR3 | |
| SCHEMBL31124667 | 0.72 | MEN1 (0.35) | MEN1KMT2AGAAKDM1AHTR2A | |
| SCHEMBL19373822 | 0.71 | — | — | |
| SCHEMBL3263053 | 0.71 | GPR3 (0.46) | MEN1KMT2AHTR2AGPR3 | |
| SCHEMBL28348254 | 0.69 | MEN1 (0.33) | MEN1KMT2AHTR2AGPR3 | |
| SCHEMBL12657209 | 0.68 | — | — | |
| SCHEMBL12215518 | 0.65 | HTR2A (0.58) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225573-A | Oxidizing in the liquid phase | BROMINE COMPOUNDS LIMITED (IL) | 1993-07-06 | — | — | US | disclosed |
| US-5015685-A | Preparation of tetrabromotetralin | BROMINE COMPOUNDS LTD. (IL) | 1991-05-14 | — | — | US | disclosed |
| US-5015685-A | Preparation of tetrabromotetralin | BROMINE COMPOUNDS LTD. (IL) | 1991-05-14 | — | — | US | disclosed |
| US-5015685-A | Preparation of tetrabromotetralin | BROMINE COMPOUNDS LTD. (IL) | 1991-05-14 | — | — | US | disclosed |