Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | F7 | P08709 | 5/20 | 0.46 |
| ▸ | F3 | P13726 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464292 | 1.00 | TBXAS1 (0.55) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL9464294 | 1.00 | TBXAS1 (0.55) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL10505227 | 0.93 | TBXAS1 (0.50) | TBXAS1LTB4RLTB4R2ALDH1A1F7 | |
| SCHEMBL10505231 | 0.93 | TBXAS1 (0.50) | TBXAS1LTB4RLTB4R2ALDH1A1F7 | |
| SCHEMBL9303907 | 0.85 | TBXAS1 (0.68) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL5176079 | 0.85 | TBXAS1 (0.68) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL849354 | 0.85 | TBXAS1 (0.68) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL849353 | 0.85 | TBXAS1 (0.68) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL8093646 | 0.85 | TBXAS1 (0.68) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 | |
| SCHEMBL8093649 | 0.85 | TBXAS1 (0.68) | TBXAS1LTB4RLTB4R2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242945-A | Antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0508690-A1 | Tetronic and thiotetronic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |