SCHEMBL9465012

SCHEMBL9465012

[CH]=Cc1ccccc1Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.50
TDP1 Q9NUW8 6/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
KDM4E B2RXH2 5/20 0.50
GAA P10253 3/20 0.50
GLA P06280 2/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 8/20 0.48
LMNA P02545 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2D6 P10635 1/20 0.48
HSD17B10 Q99714 4/20 0.46
ALOX15 P16050 5/20 0.45
HPGD P15428 4/20 0.45
CYP3A4 P08684 3/20 0.45
TSHR P16473 2/20 0.45
TP53 P04637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29940289 0.83 MAPT (0.50) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL291979 0.78 MAPT (0.50) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL96065 0.78 KMT2A (0.50) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL30463062 0.78 KMT2A (0.50) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL444976 0.75 MAPT (0.70) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL2498783 0.75 SIRT2 (0.50) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL20402998 0.75 MAPT (0.47) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL12253499 0.74 MAPT (0.45) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL5426805 0.74 MAPT (0.45) MAPTTDP1MEN1KMT2AKDM4E
SCHEMBL4884369 0.74 MAPT (0.45) MAPTTDP1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264198-B1 OPTICAL INFORMATION RECORDING MEDIUM CANON KABUSHIKI KAISHA (JP) 1993-03-03 EP disclosed
US-5178995-A Reflectance, storage stability CANON KABUSHIKI KAISHA (JP) 1993-01-12 US disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed