Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | IL1RN | P18510 | 11/20 | 0.59 |
| ▸ | ERAP2 | Q6P179 | 11/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CTSC | P53634 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465167 | 1.00 | MEN1 (0.60) | MEN1HCRTR1KMT2AIL1RNERAP2 | |
| SCHEMBL9464996 | 0.91 | ECE1 (0.54) | MEN1HCRTR1KMT2AIL1RNERAP2 | |
| SCHEMBL8725890 | 0.89 | ACE (0.71) | ACE | |
| SCHEMBL5481232 | 0.89 | ACE (0.71) | ACE | |
| SCHEMBL7397641 | 0.89 | ACE (0.71) | ACE | |
| SCHEMBL23312954 | 0.89 | ECE1 (0.67) | IL1RNERAP2ERAP1ACECTSC | |
| SCHEMBL3512696 | 0.89 | ACE (0.71) | ACE | |
| SCHEMBL30051826 | 0.88 | ACE (0.68) | ERAP2ACE | |
| SCHEMBL11940460 | 0.87 | KMT2A (0.70) | MEN1HCRTR1KMT2AIL1RNERAP2 | |
| SCHEMBL27257364 | 0.87 | KMT2A (0.70) | MEN1HCRTR1KMT2AIL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187195-A | Vasodilators; endothelin agonists; 1,7,12-trioxo,3-methyl, 4a,8,12a,12b-tetrahydroxy,6a-(2-amino-2-acylethylthio)-1,4, 4a,5,6,6a,7,12,12a,12b-decahydroanthroquinones | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0405421-A2 | Anthraquinone derivatives and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |