SCHEMBL9465261

SCHEMBL9465261

Cc1cc(C2=N[N]C=C2)on1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 5/20 0.34
TP53 P04637 4/20 0.34
HCAR2 Q8TDS4 1/20 0.33
BRD4 O60885 1/20 0.33
SLC6A3 Q01959 2/20 0.31
KMT2A Q03164 1/20 0.31
EGLN2 Q96KS0 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9465135 0.77 CHRNA1 (0.40) ALDH1A1LMNA
SCHEMBL9465688 0.70 NPC1 (0.61) CYP1A2CYP2C9CYP2C19TP53KMT2A
SCHEMBL9465148 0.67 ALDH1A1 (0.39) KDM4EALDH1A1TSHRMAPTTP53
SCHEMBL9466021 0.65 BRD4 (0.44) CYP1A2CYP2C9CYP2C19USP2ALDH1A1
SCHEMBL24307626 0.64 NPC1 (0.58) CYP1A2CYP19A1CYP2C9CYP2C19ALDH1A1
SCHEMBL9466167 0.64
SCHEMBL2272084 0.63 CYP1A2 (0.54) CYP1A2CYP19A1CYP2C9CYP2C19MAPT
SCHEMBL9465775 0.61 ESR1 (0.30)
SCHEMBL7221763 0.61 KDM4E (0.39) CYP1A2CYP19A1CYP2C9CYP2C19KDM4E
SCHEMBL9464870 0.61 PDE10A (0.40) CYP2C9KDM4EALDH1A1TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed