SCHEMBL9465639

SCHEMBL9465639

C1=C[N]C(n2ccc3ccccc32)=C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.43
PRKD3 O94806 1/20 0.42
PRKCG P05129 1/20 0.42
PRKCB P05771 1/20 0.42
PRKCA P17252 1/20 0.42
PRKACA P17612 1/20 0.42
PRKACG P22612 1/20 0.42
PRKACB P22694 1/20 0.42
PRKCH P24723 1/20 0.42
PRKCI P41743 1/20 0.42
PRKCE Q02156 1/20 0.42
PRKCQ Q04759 1/20 0.42
PRKCZ Q05513 1/20 0.42
PRKCD Q05655 1/20 0.42
PRKD1 Q15139 1/20 0.42
CDC7 O00311 1/20 0.41
CDK2 P24941 1/20 0.41
ROCK1 Q13464 1/20 0.41
CDK4 P11802 4/20 0.37
CCND1 P24385 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9465241 0.70 HTT (0.53) ROCK1MKNK1MKNK2
SCHEMBL9465640 0.70 CYP11B1 (0.41) MKNK1MKNK2MAPK8MAPK9MAPK10
SCHEMBL13052919 0.70 BIRC5 (0.59) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL9464856 0.69 BIRC5 (0.44) BIRC5PRKD3PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL15066336 0.67 BIRC5 (0.66) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL1040301 0.67
SCHEMBL170890 0.66 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL10153905 0.66 BIRC5 (0.64) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL29475118 0.66 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL29388240 0.66 RPS6KA5 (0.60) BIRC5PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed