SCHEMBL9465643

SCHEMBL9465643

Clc1ccc(C2=N[N]C=C2)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.48
CYP1A2 P05177 4/20 0.48
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
TYMS P04818 1/20 0.33
ALDH1A1 P00352 3/20 0.33
NR4A2 P43354 1/20 0.31
HCAR1 Q9BXC0 1/20 0.31
KDM4E B2RXH2 3/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
ERCC1 P07992 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
FEN1 P39748 1/20 0.31
ERCC4 Q92889 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HPGD P15428 1/20 0.31
IDO1 P14902 1/20 0.30
CCR1 P32246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293609 0.79 CYP2A6 (0.41) CYP2A6KMT2AALDH1A1KDM4EPOLB
SCHEMBL9467464 0.76 NISCH (0.39) CYP2A6CYP1A2ATMALDH1A1KDM4E
SCHEMBL7853519 0.72 NOTUM (0.40) TSHRIDO1
SCHEMBL9466201 0.71 CYP1A2 (0.45) CYP1A2ALDH1A1KDM4EMAPTHPGD
SCHEMBL29494605 0.69 CYP2A6 (1.00) CYP2A6CYP1A2KMT2AATMTYMS
SCHEMBL2473555 0.69 CYP2A6 (1.00) CYP2A6CYP1A2KMT2AATMTYMS
SCHEMBL9465431 0.68 MIF (0.38)
SCHEMBL5602065 0.67 NPC1 (0.41) CYP1A2KMT2AALDH1A1KDM4ETSHR
SCHEMBL1854697 0.67 ALDH1A1 (0.36) KMT2AALDH1A1KDM4EIDO1L3MBTL1
SCHEMBL9465269 0.66 CDK2 (0.46) CYP1A2ALDH1A1KDM4EMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed