Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.37 |
| ▸ | MGMT | P16455 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193371 | 0.80 | PDPK1 (0.41) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| Xanthine SCHEMBL9443819 | 0.79 | GDA (0.44) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| Xanthine SCHEMBL4966 | 0.79 | GDA (0.44) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| SCHEMBL29366073 | 0.79 | PDPK1 (0.44) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| SCHEMBL20611894 | 0.79 | PDPK1 (0.44) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| Xanthine SCHEMBL7044234 | 0.78 | GDA (0.42) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| SCHEMBL833645 | 0.76 | GDA (0.41) | GDAPDPK1ADORA3ADORA1MAP3K5 | |
| Isoguanine SCHEMBL29569323 | 0.76 | PDPK1 (0.66) | GDAPDPK1MAP3K5XDHCDK2 | |
| Isoguanine SCHEMBL887741 | 0.76 | PDPK1 (0.66) | GDAPDPK1MAP3K5XDHCDK2 | |
| SCHEMBL16146331 | 0.76 | DPP4 (0.61) | GDAPDPK1ADORA3ADORA1MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5213972-A | Production of thymidine and deoxyuridine, intermediates for AZT | CHEMGEN CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |
| WO-1990006312-A1 | 2',3'-DIDEOXYRIBOFURANOSIDES AND PROCESS FOR PRODUCING THEM | INSTITUT FÜR MOLEKULARBIOLOGIE UND ANALYTIK (IMA) GMBH (DE) | 1990-06-14 | — | — | WO | disclosed |