Xanthine

Xanthine

SCHEMBL4966

Oc1nc(O)c2[nH]cnc2n1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.44
PDPK1 O15530 1/20 0.44
ALDH1A1 P00352 1/20 0.41
CDK2 P24941 1/20 0.41
DPP4 P27487 1/20 0.41
PNP P00491 1/20 0.40
XDH P47989 2/20 0.38
MAP3K5 Q99683 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ADORA3 P0DMS8 2/20 0.37
ADORA2A P29274 2/20 0.37
ADORA1 P30542 2/20 0.37
BRAF P15056 2/20 0.36
PI4KA P42356 2/20 0.36
PI4K2B Q8TCG2 2/20 0.36
PI4K2A Q9BTU6 2/20 0.36
PI4KB Q9UBF8 2/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthine SCHEMBL9443819 1.00 GDA (0.44) GDAPDPK1ALDH1A1CDK2DPP4
Xanthine SCHEMBL7044234 0.98 GDA (0.42) GDAPDPK1ALDH1A1CDK2DPP4
2,6-Diaminopurine SCHEMBL6839643 0.85 PDPK1 (0.72) GDAPDPK1CDK2DPP4XDH
SCHEMBL1724116 0.83 GDA (0.41) GDAPDPK1ALDH1A1CDK2DPP4
SCHEMBL9154126 0.82 GDA (0.35) GDAPDPK1ALDH1A1CDK2DPP4
SCHEMBL2350025 0.79 GDA (0.41) GDAPDPK1ALDH1A1CDK2DPP4
SCHEMBL612211 0.79 GDA (0.41) GDAPDPK1ALDH1A1CDK2DPP4
SCHEMBL16146458 0.79 CDK2 (0.47) GDAPDPK1ALDH1A1CDK2DPP4
SCHEMBL1009011 0.79 XDH (0.56) GDAPDPK1CDK2DPP4XDH
SCHEMBL1898183 0.79 GDA (0.41) GDAPDPK1ALDH1A1CDK2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 119692 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122081155-A Pediococcus acidilactici TC-4 capable of degrading nucleoside, purine and uric acid simultaneously and application thereof 2026-05-26 CN claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US claimed
US-20260137652-A1 Composition Comprising Non-Phosphorylated Tryptamine SINTALICA S R L (IT) 2026-05-21 US claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
US-20260138935-A1 System and method for the production of chemical compounds and nutrient optimized fertilizer from animal waste products Nalari Scientific, LLC (US) 2026-05-21 US claimed
US-4189469-A Pharmaceutical compositions HOECHST AKTIENGESELLSCHAFT (DE) 1980-02-19 US claimed
EP-0001735-A1 Xanthine derivatives having antiallergic activity and pharmacological preparations containing them Aktiebolaget DRACO (SE) 1979-05-02 EP claimed
US-4141976-A XANTHINES OR THIOXANTHINES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1979-02-27 US claimed
US-4120947-A Xanthine compounds and method of treating bronchospastic and allergic diseases COOPER LABORATORIES, INC. (US) 1978-10-17 US claimed
US-4113282-A TETRANITRODIPHENYL ACETIC ACID DERIVATIVES THE MEAD CORPORATION (US) 1978-09-12 US claimed
US-4105656-A PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US claimed
US-4089959-A Long-acting xanthine bronchodilators and antiallergy agents COOPER LABORATORIES, INC. (US) 1978-05-16 US claimed
US-3977944-A Enzyme-kinetic determination of the concentration of a substrate EPPENDORF GERATEBAU NETHELER & HINZ GMBH (DT) 1976-08-31 US claimed
US-3954663-A EXTRACTION, XANTHINE DERIVATIVES TEIKOKU HORININE MFG. CO. LTD. (JA) 1976-05-04 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed