SCHEMBL946586

SCHEMBL946586

Cc1cc(CC(Cl)(Cl)CC(Cl)(Cl)Cl)c(Cl)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.33
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL943588 0.84 CD44 (0.38) CD44CYP3A4
SCHEMBL944491 0.79 CD44 (0.37) CD44CYP3A4
SCHEMBL13191797 0.77 CD44 (0.35) CD44CYP3A4
SCHEMBL14432237 0.72 CD44 (0.38) CD44CYP3A4
SCHEMBL944592 0.69
SCHEMBL195131 0.69 CD44 (0.42) CD44CYP3A4
SCHEMBL12811480 0.69 GRIN2D (0.47) CD44CYP3A4
SCHEMBL22295234 0.68 CD44 (0.38) CD44CYP3A4
SCHEMBL17466157 0.67 CD44 (0.41) CD44CYP3A4
SCHEMBL13696818 0.67 IDO1 (0.46) CD44CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875753-B2 formed by reacting aryldiazonium bromide with vinylidene chloride in presence of copper salt and bromide source BAYER CROPSCIENCE AG (DE) 2011-01-25 US disclosed
US-20100234651-A1 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234651-A1 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof AR, AHR, ADRA2C CD44 4648/4885CYP3A4 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.