Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024618 | 0.95 | KMT2A (0.42) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL9465547 | 0.92 | STAT3 (0.42) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL2562490 | 0.86 | CYP3A4 (0.48) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL30609565 | 0.83 | KMT2A (0.49) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL22657517 | 0.83 | KMT2A (0.49) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL2798912 | 0.82 | ALDH1A1 (0.41) | CA12CA1CA9ALDH1A1LMNA | |
| SCHEMBL24719153 | 0.82 | KMT2A (0.45) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL16637582 | 0.82 | CA12 (0.41) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL13160696 | 0.82 | KMT2A (0.47) | KMT2ASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL15286533 | 0.80 | KMT2A (0.45) | KMT2ASMN1; SMN2CA1STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056568-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-09-14 | — | — | EP | disclosed |
| EP-0412110-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1993-07-07 | — | — | EP | disclosed |
| US-5206229-A | Inhibit cell proliferation, antiinflammatory, treating imbalance of immune system | LEO PHARMACEUTICAL PRODUCTS LTD (DK) | 1993-04-27 | — | — | US | disclosed |
| EP-0412110-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1991-02-13 | — | — | EP | disclosed |
| WO-1989010351-A1 | NOVEL VITAMIN D ANALOGUES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LØVENS KEMIS (DK) | 1989-11-02 | — | — | WO | disclosed |
| EP-0007180-B1 | PROSTAGLANDIN ANALOGUE TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-03-30 | — | — | EP | disclosed |
| US-4294972-A | ANTIULCER AGENTS, CARDIOVASCULAR DISORDERS | BEECHAM GROUP LIMITED (GB) | 1981-10-13 | — | — | US | disclosed |
| EP-0007180-A1 | Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them | BEECHAM GROUP PLC (GB) | 1980-01-23 | — | — | EP | disclosed |