Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359162 | 1.00 | LMNA (0.68) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL9756758 | 1.00 | LMNA (0.68) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL5702262 | 1.00 | LMNA (0.68) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL11363905 | 1.00 | LMNA (0.68) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL11574108 | 0.97 | LMNA (0.74) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL16548164 | 0.97 | LMNA (0.65) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL114059 | 0.97 | LMNA (0.63) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL3995713 | 0.97 | LMNA (0.63) | LMNABLMPTPN1TSHRMEN1 | |
| Alcohol SCHEMBL11707824 | 0.95 | LMNA (0.62) | LMNABLMPTPN1TSHRMEN1 | |
| SCHEMBL20503660 | 0.92 | LMNA (0.63) | LMNABLMPTPN1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316374-B1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | claimed |
| EP-0316374-A1 | OPTICALLY ACTIVE COMPOUNDS. | HOFFMANN LA ROCHE (CH) | 1989-05-24 | — | — | EP | claimed |
| WO-1988008838-A1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1988-11-17 | — | — | WO | claimed |
| US-5243096-A | Optically active pentane derivatives and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-09-07 | — | — | US | disclosed |
| US-5136061-A | Optically active pentane derivatives and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0316374-B1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | disclosed |
| EP-0316374-A1 | OPTICALLY ACTIVE COMPOUNDS. | HOFFMANN LA ROCHE (CH) | 1989-05-24 | — | — | EP | disclosed |
| WO-1988008838-A1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1988-11-17 | — | — | WO | disclosed |
| US-4277610-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1981-07-07 | — | — | US | disclosed |
| US-4191842-A | Protected alcohols | HOFFMANN-LA ROCHE INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4180682-A | Unsaturated alcohols having an ether protected group | HOFFMANN-LA ROCHE INC. (US) | 1979-12-25 | — | — | US | disclosed |
| US-4086249-A | Tetramethyl chromanyl pentane amide | HOFFMANN-LA ROCHE INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4076739-A | Synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4051153-A | Intermediates in the synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-4041058-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-4026907-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018799-A | INTERMEDIATES FOR TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016178-A | Synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1977-04-05 | — | — | US | disclosed |
| US-4003919-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3947473-A | (6-HYDROXY-CHROMAN-2-YL) CARBOXYLIC ACID DERIVATIVES | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |