Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.74 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.72 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.72 |
| ▸ | ITGAL | P20701 | 6/20 | 0.72 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.66 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | HPGDS | O60760 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.63 |
| ▸ | ACE | P12821 | 1/20 | 0.63 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.62 |
| ▸ | TACR1 | P25103 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828342 | 1.00 | ERAP2 (0.74) | ERAP2ITGB2ICAM1ITGALERAP1 | |
| SCHEMBL9466705 | 0.93 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL5191302 | 0.93 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL30616778 | 0.93 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL5259129 | 0.93 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL11870861 | 0.92 | ERAP2 (0.76) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL22206878 | 0.91 | ITGB2 (0.77) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL22206876 | 0.91 | ITGB2 (0.77) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL23092632 | 0.89 | ITGB2 (0.81) | ERAP2ITGB2ICAM1ITGALCA12 | |
| SCHEMBL21623652 | 0.89 | ERAP2 (0.72) | ERAP2ITGB2ICAM1ITGALCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014726-A1 | TREATMENT FOR LIVER REGENERATION | XENEXUS PHARMACEUTICALS PTY. LTD. (AU) | 2020-01-23 | — | — | WO | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |