Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27076467 | 0.83 | ALPI (0.47) | MAPTIDO1 | |
| SCHEMBL7680917 | 0.83 | ACE (0.47) | GRM7ACE | |
| SCHEMBL27076468 | 0.83 | ALPI (0.47) | MAPTIDO1 | |
| Hydrochloric Acid SCHEMBL8590375 | 0.82 | ALPI (0.46) | IDO1 | |
| Hydrochloric Acid SCHEMBL8590499 | 0.82 | ALPI (0.46) | IDO1 | |
| Hydrochloric Acid SCHEMBL8590359 | 0.82 | ALPI (0.46) | IDO1 | |
| SCHEMBL8589263 | 0.78 | TSHR (0.39) | MAPTGRM7IDO1MTNR1AMTNR1B | |
| SCHEMBL8587688 | 0.78 | TSHR (0.39) | MAPTGRM7IDO1MTNR1AMTNR1B | |
| SCHEMBL8590527 | 0.77 | IDO1 (0.50) | MAPTIDO1MTNR1AMTNR1BKDM4E | |
| SCHEMBL1340255 | 0.75 | DGAT1 (0.47) | MAPTCYP19A1IDO1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |