Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068638 | 0.80 | ATM (0.33) | CHRNA7ABCB1TSHRATMMAPT | |
| SCHEMBL5185255 | 0.80 | POLB (0.34) | POLBTRPA1KDM1AMAOAMAOB | |
| SCHEMBL7199456 | 0.78 | CHRNA7 (0.41) | CHRNA7TRPA1KDM1AMAOAMAOB | |
| SCHEMBL222998 | 0.77 | CHRNA7 (0.35) | CHRNA7TRPA1TSHRKDM1AMAOA | |
| SCHEMBL7511837 | 0.77 | KDM1A (0.40) | CHRNA7TRPA1TSHRKDM1AMAOA | |
| SCHEMBL5576897 | 0.77 | KDM1A (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL8077336 | 0.77 | KDM1A (0.38) | KDM1AMAOAMAOB | |
| SCHEMBL7430840 | 0.77 | KDM1A (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL4234394 | 0.77 | POLB (0.37) | POLBABCB1TSHRATMMAPT | |
| Hydrogen Sulfide SCHEMBL8857190 | 0.75 | CHRNA7 (0.34) | CHRNA7TRPA1TSHRKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198570-A | Aryloxyfluoroether esters, processes for preparation thereof, and alcohols and acids formed therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-30 | — | — | US | disclosed |