Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.38 |
| ▸ | MAOA | P21397 | 18/20 | 0.38 |
| ▸ | MAOB | P27338 | 18/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185255 | 0.80 | POLB (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL7511837 | 0.77 | KDM1A (0.40) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL1074533 | 0.77 | KDM1A (0.40) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL9466795 | 0.77 | CHRNA7 (0.34) | KDM1AMAOAMAOB | |
| SCHEMBL5576897 | 0.77 | KDM1A (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL7430840 | 0.77 | KDM1A (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL9220720 | 0.77 | KDM1A (0.35) | KDM1AMAOAMAOBHTR2AHTR2C | |
| Methane SCHEMBL16507862 | 0.75 | KDM1A (0.39) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL3786291 | 0.75 | IDO1 (0.38) | KDM1AMAOAMAOB | |
| Propane SCHEMBL23045273 | 0.74 | KDM1A (0.43) | KDM1AMAOAMAOBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| EP-1027387-A1 | DOUBLE REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-16 | — | — | EP | disclosed |
| EP-1000123-A2 | USE OF REACTIVE DYES FOR DYEING HAIR | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999023169-A1 | DOUBLE REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-14 | — | — | WO | disclosed |
| WO-1999005222-A2 | USE OF REACTIVE DYES FOR DYEING HAIR | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |