SCHEMBL9466845

SCHEMBL9466845

CCCCCCCCCCCCCCCCCCNCCCCCCCCCCCCCCCCCC.COS(=O)(=O)O

nearest known ligand 0.56

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
TSHR P16473 1/20 0.56
CA2 P00918 3/20 0.53
CA1 P00915 2/20 0.53
S1PR2 O95136 5/20 0.52
S1PR4 O95977 5/20 0.52
S1PR1 P21453 5/20 0.52
S1PR3 Q99500 5/20 0.52
S1PR5 Q9H228 1/20 0.52
EPHX1 P07099 4/20 0.50
CA12 O43570 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
PPARA Q07869 2/20 0.47
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15758487 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA2CA1S1PR2
SCHEMBL11581874 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA2CA1S1PR2
SCHEMBL27990209 0.92 ALDH1A1 (0.48) ALDH1A1TSHRCA2CA1S1PR2
SCHEMBL5446119 0.92 TSHR (0.50) ALDH1A1TSHRCA2CA1S1PR2
Dodecane SCHEMBL27985012 0.89 EPHX1 (0.48) TSHRCA2CA1EPHX1CA12
Octane SCHEMBL10634241 0.89 EPHX1 (0.48) TSHRCA2CA1EPHX1CA12
Sulfuric Acid SCHEMBL2214631 0.86 ALDH1A1 (0.68) ALDH1A1TSHRCA2CA1S1PR2
Sulfuric Acid SCHEMBL6397070 0.86 ALDH1A1 (0.68) ALDH1A1TSHRCA2CA1S1PR2
Sulfuric Acid SCHEMBL9422571 0.86 ALDH1A1 (0.68) ALDH1A1TSHRCA2CA1S1PR2
Sulfuric Acid SCHEMBL4050513 0.86 ALDH1A1 (0.68) ALDH1A1TSHRCA2CA1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5212037-A TONER PROCESS WITH METAL OXIDES XEROX CORPORATION (US) 1993-05-18 US disclosed
US-5051196-A Fabric softener of a quaternary ammonium salts and crosslinked polysiloxanes COLGATE-PALMOLIVE CO. (US) 1991-09-24 US disclosed
EP-0354856-A2 New softening compositions and methods for making and using same Colgate-Palmolive Company (US) 1990-02-14 EP disclosed