Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.86 |
| ▸ | MAOB | P27338 | 9/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920 | 0.93 | TAAR1 (1.00) | TAAR1MAOBCYP1A2CYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL11513889 | 0.90 | TAAR1 (0.95) | TAAR1MAOBCYP1A2CYP2A6HTR2A | |
| SCHEMBL6532602 | 0.87 | MAOB (0.73) | TAAR1MAOBCYP1A2CYP2A6HTR2A | |
| SCHEMBL10336304 | 0.86 | TAAR1 (0.86) | TAAR1MAOBCYP1A2CYP2A6HTR2A | |
| SCHEMBL2776957 | 0.82 | TP53 (0.56) | TAAR1CYP2A6ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL1702558 | 0.82 | TP53 (0.56) | TAAR1CYP2A6ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6486399 | 0.80 | CYP3A4 (0.58) | TAAR1MAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL13814906 | 0.80 | HRH3 (0.74) | TAAR1CYP2A6 | |
| SCHEMBL19139628 | 0.80 | CYP3A4 (0.58) | TAAR1MAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL19139640 | 0.80 | CYP3A4 (0.58) | TAAR1MAOBKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |
| US-5232946-A | Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency | DR. KARL THOMAE GMBH (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0400011-A1 | NEW PHENYLETHANOLAMINES. | BOEHRINGER INGELHEIM VETMED (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0375791-A1 | Phenyl ethanol amines, their use as pharmaceutical compounds and as performance stimulants in animals, as well as processes for their preparation | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1990-07-04 | — | — | EP | disclosed |
| WO-1990006299-A1 | NEW PHENYLETHANOLAMINES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1990-06-14 | — | — | WO | disclosed |