Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16544040 | 0.92 | GFER (0.65) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL224548 | 0.90 | TAAR1 (0.72) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL172790 | 0.89 | TAAR1 (0.71) | MAOBTAAR1HTR2ACYP2A6BACE1 | |
| Hydrochloric Acid SCHEMBL2538131 | 0.87 | TAAR1 (0.68) | MAOBTAAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL4839859 | 0.87 | TAAR1 (0.86) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL9467191 | 0.87 | TAAR1 (0.86) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3168355 | 0.87 | BLM (0.74) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| Iodide SCHEMBL29101247 | 0.87 | TAAR1 (0.68) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3668004 | 0.87 | BLM (0.74) | MAOBTAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL21540874 | 0.85 | LOXL2 (0.74) | MAOBTAAR1HTR2ACYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979566-B2 | Method of treatment of viral infection including HIV using water soluble fullerenes—III | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-27 | — | — | US | disclosed |
| US-20040044062-A1 | Method of treatment of viral infection including HIV using water soluble fullerenes - III | FRIEDMAN SIMON H (US) | 2004-03-04 | — | — | US | disclosed |
| US-6613771-B2 | Prevent human retroviral reproduction, infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-02 | — | — | US | disclosed |
| US-20010041801-A1 | Water soluble fullerenes with antiviral activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-11-15 | — | — | US | disclosed |
| US-6204391-B1 | PREVENT REPRODUCTION OF HUMAN RETROVIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-03-20 | — | — | US | disclosed |
| WO-1995019949-A1 | WATER SOLUBLE FULLERENES WITH ANTIVIRAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044062-A1 | Method of treatment of viral infection including HIV using water soluble fullerenes - III | CD4, RPP30, CASP3 | MAOB 2820/4885TAAR1 4874/4885HTR2A 4366/4885 |
| US-20010041801-A1 | Water soluble fullerenes with antiviral activity | ZC3HAV1, RPL35, SARS1 | MAOB 2970/4885TAAR1 4875/4885HTR2A 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.