Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926031 | 0.77 | CRBN (0.48) | CRBNTSHRNPSR1 | |
| SCHEMBL634197 | 0.72 | — | — | |
| SCHEMBL23645791 | 0.72 | — | — | |
| SCHEMBL7182820 | 0.68 | CA1 (0.30) | — | |
| SCHEMBL277991 | 0.67 | CRBN (0.41) | CRBNTSHRNPSR1DDB1 | |
| SCHEMBL493044 | 0.65 | — | — | |
| SCHEMBL11860898 | 0.65 | — | — | |
| SCHEMBL16556682 | 0.65 | — | — | |
| SCHEMBL10218521 | 0.65 | — | — | |
| SCHEMBL9388661 | 0.65 | CYP3A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202455-A | Heating liquid mixture of acid and ammonia with phosphoric acid-based catalyst and adsorbent | HUELS AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| EP-0491129-A2 | Process for the nitrilation of aliphatic dicarboxylic acids in the liquid phase | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-06-24 | — | — | EP | disclosed |