SCHEMBL94674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4472661	0.83	NPC1 (0.82)	ALDH1A1MAPTNPC1LMNARAB9A
	SCHEMBL95412	0.81	HDAC1 (0.52)	ALDH1A1MAPTLMNASMN1; SMN2TP53
	SCHEMBL10143992	0.81	NPC1 (1.00)	ALDH1A1MAPTNPC1LMNARAB9A
	SCHEMBL2960979	0.78	USP2 (0.58)	ALDH1A1MAPTLMNASMN1; SMN2CYP1A2
	SCHEMBL5543735	0.78	HPGD (0.61)	ALDH1A1MAPTNPC1LMNARAB9A
	SCHEMBL95772	0.78	HDAC1 (0.52)	TP53LPAR1LPAR5HDAC1HDAC6
	SCHEMBL31517003	0.74	MAPT (0.63)	ALDH1A1MAPTNPC1LMNARAB9A
	SCHEMBL128504	0.73	NQO1 (0.74)	ALDH1A1MAPTNPC1SMN1; SMN2KDM4E
	SCHEMBL25138742	0.72	HDAC1 (0.71)	ALDH1A1MAPTLMNASMN1; SMN2LPAR1
	SCHEMBL3757670	0.72	HPGD (0.58)	ALDH1A1MAPTNPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.