Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485076 | 0.97 | NQO1 (0.70) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL18725069 | 0.93 | NQO1 (0.64) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL6292553 | 0.93 | LTA4H (0.65) | NQO1TSHRTDP1LTA4HKDM4E | |
| Zinc Chloride SCHEMBL27752361 | 0.91 | NQO1 (0.61) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL27616183 | 0.86 | NQO1 (0.88) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.86 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.86 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL27691078 | 0.83 | NQO1 (0.50) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL11794798 | 0.83 | NQO1 (0.93) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL58858 | 0.80 | NQO1 (0.67) | NQO1TSHRTDP1LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218022-A1 | ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-04 | — | — | US | claimed |
| CN-118271331-A | Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation | 赣江中药创新中心 | 2024-07-02 | — | — | CN | claimed |
| CN-116655515-B | N-alkoxy-1-acyl-1H-pyrrole-2-amide compound and application thereof | 中山大学 | 2024-05-03 | — | — | CN | claimed |
| CN-114276411-B | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2024-02-09 | — | — | CN | claimed |
| CN-116655515-A | N-alkoxy-1-acyl-1H-pyrrole-2-amide compound and application thereof | 中山大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116514790-A | Tri-aromatic heterocyclic piperazine small molecular organic compound targeting STAT3 and application thereof | 华东师范大学 | 2023-08-01 | — | — | CN | claimed |
| CN-114276411-A | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2022-04-05 | — | — | CN | claimed |
| CN-113582956-A | Sulfur-containing aryl carbon glycoside compound and synthesis method and application thereof | 华东师范大学 | 2021-11-02 | — | — | CN | claimed |
| CN-111848675-B | Tetrahydroquinoline framework chiral phosphine-nitrogen ligand and preparation method and application thereof | 中国科学院化学研究所 | 2021-09-07 | — | — | CN | claimed |
| CN-108368041-B | (R) -N- (adamantyl-2-yl) pyrrolidine-2-carboxamide derivatives for cosmetic use | 帝斯曼知识产权资产管理有限公司 | 2021-09-07 | — | — | CN | claimed |
| EP-0126986-A1 | Process for producing N-alkylated dipeptides and their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-05 | — | — | EP | claimed |
| EP-0126234-A2 | 1,2,3-Thiadiazol-3-in-5-ylidene ureas, their preparation and compositions as plant-growth regulators and defoliants | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | claimed |
| EP-0117448-A1 | Process for the preparation of N-alkylated amino acids and their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-05 | — | — | EP | claimed |
| EP-0116276-A2 | Derivatives of spirocyclic amino-acids, their process of preparation, agents containing them, and their use, as well as spirocyclic amino-acids as intermediaries and their process of preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-22 | — | — | EP | claimed |
| EP-0113880-A2 | Derivatives from 2-azabicyclo(2.2.1)heptane, process for their preparation, agents containing them and their use, and 2-azabicyclo(2.2.1)heptane derivatives as intermediates, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-25 | — | — | EP | claimed |
| EP-0031304-B1 | PIPERIDINE DERIVATIVES AS STABILIZERS FOR SYNTHETIC POLYMERS | CIBA-GEIGY S.p.A. (IT) | 1984-06-13 | — | — | EP | claimed |
| EP-0090362-A2 | Derivatives of cycloalka(c)pyrrole-carboxylic acids, process for their preparation, agents containing them and their use, as well as cycloalka(c)pyrrole-carboxylic acids as intermediates, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | claimed |
| EP-0090341-A2 | Spiro-(4,(3+n))-2-aza-alkan-3-carboxylic-acid derivatives, process for their preparation,agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | claimed |
| EP-0034430-B1 | PROCESS FOR PREPARING ARYLACETALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | claimed |
| US-4369321-A | Piperidine derivatives which are stabilizers for synthetic polymers | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1983-01-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218022-A1 | ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS | VIP, SGTA, NGLY1 | NQO1 4559/4885TSHR 459/4885TDP1 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.