Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.52 |
| ▸ | UTRN | P46939 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593382 | 0.88 | NPC1 (0.58) | MAPTVSIRNPC1RAB9AALDH1A1 | |
| SCHEMBL28173331 | 0.86 | HDAC6 (0.62) | HDAC6MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL24295224 | 0.84 | GPR119 (0.62) | MAPTVSIRNPC1RAB9AALDH1A1 | |
| SCHEMBL5595554 | 0.84 | NPC1 (0.69) | HDAC6MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL28028562 | 0.83 | SMN1; SMN2 (0.57) | HDAC6MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29820037 | 0.83 | GPR119 (0.61) | MAPTVSIRNPC1RAB9AALDH1A1 | |
| SCHEMBL29819610 | 0.83 | GPR119 (0.61) | MAPTVSIRNPC1RAB9AALDH1A1 | |
| SCHEMBL590701 | 0.83 | GPR119 (0.61) | MAPTVSIRNPC1RAB9AALDH1A1 | |
| SCHEMBL9467880 | 0.83 | HDAC6 (0.57) | HDAC6MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL24038237 | 0.83 | HDAC6 (0.56) | HDAC6MAPTVSIRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216110-A | Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5194562-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| US-5104960-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |