Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643618 | 0.91 | NR3C2 (0.65) | NR3C2CACNA1CCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9580964 | 0.90 | CYP2C9 (0.51) | NR3C2CACNA1CKDM4EHSD17B10AXL | |
| SCHEMBL9644465 | 0.90 | NR3C2 (0.77) | NR3C2CACNA1CKDM4EMAPTCYP1A2 | |
| SCHEMBL9580965 | 0.88 | CYP2C9 (0.48) | NR3C2CACNA1CKDM4EHSD17B10AXL | |
| SCHEMBL9463384 | 0.86 | NR3C2 (0.54) | NR3C2CACNA1CKDM4EHSD17B10AXL | |
| SCHEMBL9463356 | 0.85 | NR3C2 (0.47) | NR3C2CACNA1CKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9140284 | 0.85 | NR3C2 (0.44) | NR3C2CACNA1CKDM4EHSD17B10AXL | |
| SCHEMBL8923705 | 0.85 | NR3C2 (0.52) | NR3C2CACNA1CKDM4EALDH1A1MAPT | |
| SCHEMBL7162892 | 0.85 | NR3C2 (0.52) | NR3C2CACNA1CKDM4EALDH1A1MAPT | |
| SCHEMBL9468051 | 0.84 | MAPT (0.56) | NR3C2CACNA1CKDM4EHSD17B10AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204472-A | For preparing inotropic agents; substituted dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| US-5100900-A | Inotropic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |