Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162892 | 1.00 | NR3C2 (0.52) | NR3C2METCACNA1CKDM4EALDH1A1 | |
| SCHEMBL27438736 | 0.90 | CACNA1C (0.44) | NR3C2METCACNA1CKDM4EALDH1A1 | |
| SCHEMBL6931471 | 0.89 | NR3C2 (0.67) | NR3C2METCACNA1CKDM4EALDH1A1 | |
| SCHEMBL7877495 | 0.89 | NR3C2 (0.67) | NR3C2METCACNA1CKDM4EALDH1A1 | |
| SCHEMBL9123412 | 0.87 | NR3C2 (0.54) | NR3C2CACNA1C | |
| SCHEMBL9467948 | 0.85 | NR3C2 (0.62) | NR3C2METCACNA1CKDM4EALDH1A1 | |
| SCHEMBL9643618 | 0.83 | NR3C2 (0.65) | NR3C2CACNA1C | |
| SCHEMBL7275395 | 0.83 | NR3C2 (0.55) | NR3C2METCACNA1CKDM4EALDH1A1 | |
| SCHEMBL9644465 | 0.83 | NR3C2 (0.77) | NR3C2METCACNA1CKDM4EMAPT | |
| SCHEMBL9463271 | 0.81 | NR3C2 (0.44) | NR3C2METALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5653998-A | Injectable liposomal pharmaceutical preparations | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-05 | — | — | US | disclosed |
| CN-1100418-A | 2-amino-5-cyano-4-quinolyldihydropyridine esters, processes for their preparation and their use in medicaments | BAYER AG (DE) | 1995-03-22 | — | — | CN | disclosed |