Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GMNN | O75496 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | CETP | P11597 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.53 |
| ▸ | CCR6 | P51684 | 2/20 | 0.53 |
| ▸ | UBE2N | P61088 | 2/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17142330 | 1.00 | MAPT (0.53) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL9468647 | 1.00 | MAPT (0.53) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL17142346 | 0.98 | MAPT (0.50) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL17142338 | 0.92 | GRIK1 (0.46) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL27081837 | 0.92 | GRIK1 (0.46) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL19818183 | 0.92 | GRIK1 (0.46) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL9468236 | 0.85 | MEN1 (0.56) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL9468124 | 0.85 | MEN1 (0.56) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL10428039 | 0.85 | MEN1 (0.51) | MAPTKMT2ABLMMEN1GMNN | |
| SCHEMBL9468017 | 0.84 | GRIK1 (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208260-A | Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder | G. D. SEARLE & CO. (US) | 1993-05-04 | — | — | US | claimed |
| US-5208260-A | Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder | G. D. SEARLE & CO. (US) | 1993-05-04 | — | — | US | disclosed |