Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GMNN | O75496 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | CETP | P11597 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.53 |
| ▸ | CCR6 | P51684 | 2/20 | 0.53 |
| ▸ | UBE2N | P61088 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468124 | 1.00 | MEN1 (0.56) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL9468647 | 0.85 | MAPT (0.53) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL17142330 | 0.85 | MAPT (0.53) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL9467958 | 0.85 | MAPT (0.53) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL10428039 | 0.85 | MEN1 (0.51) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL9467313 | 0.84 | TAS1R3 (0.36) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL9468076 | 0.84 | TAS1R3 (0.36) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL17142346 | 0.83 | MAPT (0.50) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL28683272 | 0.80 | MEN1 (0.55) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL3375007 | 0.79 | MEN1 (0.53) | MEN1KMT2AFAAHCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208260-A | Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder | G. D. SEARLE & CO. (US) | 1993-05-04 | — | — | US | disclosed |