SCHEMBL9468

SCHEMBL9468

CCC(=O)O[C@]1(C(=O)SCF)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](OC(=O)c3ccco3)C[C@@]21C

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 14/20 0.76
PGR P06401 5/20 0.76
AR P10275 5/20 0.76
NR3C2 P08235 2/20 0.76
PTGS1 P23219 2/20 0.76
CNR1 P21554 1/20 0.76
CYP3A4 P08684 5/20 0.72
ADORA3 P0DMS8 3/20 0.72
NR1I2 O75469 1/20 0.72
CHRM1 P11229 1/20 0.56
ADRA1A P35348 1/20 0.56
MEN1 O00255 1/20 0.49
ALOX15 P16050 1/20 0.49
KMT2A Q03164 1/20 0.49
HIF1A Q16665 2/20 0.47
CYP1A2 P05177 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15555726 0.99 NR3C1 (0.74) NR3C1PGRARNR3C2PTGS1
SCHEMBL377593 0.96 NR3C1 (0.71) NR3C1PGRARNR3C2PTGS1
Butanol SCHEMBL2067053 0.96 NR3C1 (0.71) NR3C1PGRARNR3C2PTGS1
Dimethylformamide SCHEMBL378085 0.96 NR3C1 (0.70) NR3C1PGRARNR3C2PTGS1
SCHEMBL158996 0.94 NR3C1 (0.70) NR3C1PGRARNR3C2PTGS1
SCHEMBL16474144 0.91 NR3C1 (0.82) NR3C1PGRARNR3C2PTGS1
SCHEMBL13581363 0.90 NR3C1 (0.83) NR3C1PGRARNR3C2PTGS1
SCHEMBL4284 0.90 NR3C1 (0.83) NR3C1PGRARNR3C2PTGS1
SCHEMBL16479362 0.89 NR3C1 (0.80) NR3C1PGRARNR3C2PTGS1
Acetone SCHEMBL14645259 0.88 NR3C1 (0.81) NR3C1PGRARNR3C2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6795 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-05-14 US claimed
EP-4739294-A1 AN INHALABLE FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA Norton (Waterford) Limited (IE) 2026-05-13 EP claimed
EP-4739295-A1 AN INHALABLE FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA Norton (Waterford) Limited (IE) 2026-05-13 EP claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-12616654-B2 Stainless steel can for pressurised metered dose inhalers CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-05 US claimed
US-12616803-B2 Apparatus for dispensing inhalant medicament METOPI PHARMACEUTICALS, INC. (US) 2026-05-05 US claimed
EP-4732870-A2 BLISTER PACK AND INHALER COMPRISING THE SAME Norton (Waterford) Limited (IE) 2026-04-29 EP claimed
EP-3125943-B1 PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES MERCK SHARP & DOHME LLC (US) 2026-04-22 EP claimed
EP-4487892-B1 BLISTER PACK AND INHALER COMPRISING THE SAME NORTON WATERFORD LTD (IE) 2026-04-15 EP claimed
EP-4288132-B1 CAPSULE INHALERS KNIGHTPOINT LLC (US) 2026-04-01 EP claimed
US-20070219223-A1 Compositions and methods for treating respiratory disorders ENDACEA, INC. (US) 2007-09-20 US claimed
WO-2007103970-A2 COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS ENDACEA, INC. (US) 2007-09-13 WO claimed
US-20070202054-A1 Inhalant Formulation Containing Sulfoalkyl Ether Cyclodextrin and Corticosteroid CYDEX PHARMACEUTICALS, INC. 2007-08-30 US claimed
US-20050022806-A1 Medicament dispenser GLAXO GROUP LIMITED (GB) 2005-02-03 US claimed
EP-1487417-A2 DRY POWDER MEDICAMENT FORMULATIONS GLAXO GROUP LIMITED (GB) 2004-12-22 EP claimed
US-20040241232-A1 Dry powder medicament formulations GLAXO GROUP LIMITED (GB) 2004-12-02 US claimed
JP-2004528151-A 2004-09-16 JP claimed
EP-1395320-A2 MEDICAMENT DISPENSER GLAXO GROUP LIMITED (GB) 2004-03-10 EP claimed
WO-2003024396-A2 DRY POWDER MEDICAMENT FORMULATIONS GLAXO GROUP LIMITED (GB) 2003-03-27 WO claimed
WO-2002100469-A2 MEDICAMENT DISPENSER FOR CONTAINERS OF VARYING SIZES GLAXO GROUP LIMITED (GB) 2002-12-19 WO claimed