Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467942 | 1.00 | LMNA (0.40) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9467370 | 1.00 | LMNA (0.40) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9467021 | 1.00 | LMNA (0.40) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL11102573 | 0.80 | LMNA (0.40) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL14797181 | 0.80 | LMNA (0.40) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9727323 | 0.80 | LMNA (0.40) | LMNATHRBCA2CA1MMP1 | |
| Methyl Alcohol SCHEMBL28458852 | 0.78 | LMNA (0.50) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9293043 | 0.76 | LMNA (0.35) | LMNATHRBCA2CA1MMP1 | |
| Perflenapent SCHEMBL10496510 | 0.73 | LMNA (0.53) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL6190368 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254660-A | Polyurethanes, fluoropolymers | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |
| EP-0540976-A1 | Use of polyisocyanate solutions for the impregnation of mineral substrates | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |