Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468238 | 0.86 | ADRB2 (0.65) | ADRB2ADRB1ADRB3 | |
| SCHEMBL30869024 | 0.84 | ADRB2 (0.78) | ADRB2ADRB1ADRB3LMNACYP3A4 | |
| SCHEMBL30869015 | 0.81 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL9468374 | 0.81 | ADRB2 (0.55) | ADRB2ADRB1ADRB3 | |
| SCHEMBL15856359 | 0.80 | ADRB2 (0.80) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL5382315 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL14030755 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9467104 | 0.79 | ADRB2 (0.68) | ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9177524 | 0.78 | ADRB2 (0.52) | ADRB2ADRB1ADRB3LMNACYP3A4 | |
| SCHEMBL4463397 | 0.78 | ADRB2 (0.50) | ADRB2ADRB1ADRB3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232946-A | Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency | DR. KARL THOMAE GMBH (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0375791-A1 | Phenyl ethanol amines, their use as pharmaceutical compounds and as performance stimulants in animals, as well as processes for their preparation | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1990-07-04 | — | — | EP | disclosed |