Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.46 |
| ▸ | FDPS | P14324 | 12/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963211 | 0.86 | TSHR (0.47) | — | |
| SCHEMBL11184961 | 0.83 | LPAR3 (0.65) | LPAR3LPAR2FDPS | |
| SCHEMBL78519 | 0.83 | LPAR3 (0.65) | LPAR3LPAR2FDPS | |
| SCHEMBL1011737 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL7909080 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL11897647 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL4818012 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL11081456 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL3761314 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL5834610 | 0.81 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252324-A | Stabilized silicone oil product | ISP INVESTMENTS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-5169623-A | Blend of silicone and in situ polymerized, water soluble vinyl monomer | ISP INVESTMENTS INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5169622-A | Hair and skin care compositions containing discrete microdroplets of an oil in water stabilized by in situ copolymerization of a water-soluble vinyl monomer and a water-soluble acryl comonomer | ISP INVESTMENTS INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-4842850-A | SHAMPOO | THE PROCTER & GAMBLE COMPANY (US) | 1989-06-27 | — | — | US | disclosed |