Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468527 | 0.90 | AGTR1 (0.33) | AGTR1PTPN1 | |
| SCHEMBL9468510 | 0.82 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9468535 | 0.82 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9154364 | 0.81 | — | — | |
| SCHEMBL9468604 | 0.81 | AGTR1 (0.39) | AGTR1PTPN1 | |
| SCHEMBL9480594 | 0.79 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9468570 | 0.77 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9308923 | 0.77 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9468237 | 0.76 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9468578 | 0.76 | AGTR1 (0.40) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| US-5219857-A | Method of treating cognitive and related neural behavioral problems | AMERICAN CYANAMID COMPANY (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |
| US-5126340-A | Antidepressants | AMERICAN CYANAMID COMPANY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4963553-A | TREATING COGNITIVE AND NEURAL BEHAVIORAL PROBLEMS IN MAMMALS | AMERICAN CYANAMID CO. (US) | 1990-10-16 | — | — | US | disclosed |