Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468535 | 0.92 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9468062 | 0.84 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9246337 | 0.84 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL9468171 | 0.83 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9154675 | 0.77 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL8545586 | 0.76 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9468052 | 0.76 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9481760 | 0.76 | AGTR1 (0.44) | AGTR1 | |
| Hydrazine SCHEMBL9539110 | 0.75 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9310410 | 0.75 | AGTR1 (0.42) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252593-A | Hypotensive agents, cognition activators | GLAXO GROUP LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0514217-A1 | Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |