Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 3/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9469940 | 0.80 | GAA (0.51) | LSSGLATSHRRXFP1GAA | |
| SCHEMBL3215158 | 0.78 | LSS (0.78) | LSSGLATSHRRXFP1NPC1 | |
| SCHEMBL3215152 | 0.78 | LSS (0.78) | LSSGLATSHRRXFP1NPC1 | |
| Hydrochloric Acid SCHEMBL9469303 | 0.76 | LSS (0.76) | LSSGLATSHRRXFP1NPC1 | |
| SCHEMBL9469387 | 0.76 | GAA (0.47) | LSSGLATSHRRXFP1NPC1 | |
| SCHEMBL3215242 | 0.76 | TSHR (0.56) | LSSGLATSHRRXFP1MAPT | |
| SCHEMBL13429317 | 0.76 | GAA (0.47) | LSSGLATSHRRXFP1NPC1 | |
| SCHEMBL3215247 | 0.76 | TSHR (0.56) | LSSGLATSHRRXFP1MAPT | |
| SCHEMBL3842055 | 0.75 | TSHR (0.45) | LSSGLATSHRRXFP1NPC1 | |
| Hydrochloric Acid SCHEMBL9469012 | 0.75 | TSHR (0.59) | LSSGLATSHRRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |