Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13429317 | 1.00 | GAA (0.47) | GAAATMLSSTSHRRXFP1 | |
| Hydrochloric Acid SCHEMBL9469940 | 0.86 | GAA (0.51) | GAAATMLSSTSHRRXFP1 | |
| SCHEMBL9469749 | 0.83 | GAA (0.50) | GAAATMLSSTSHRRXFP1 | |
| SCHEMBL3840344 | 0.76 | CNR2 (0.46) | GAAATMTSHRRXFP1CHRNA7 | |
| SCHEMBL3840340 | 0.76 | CNR2 (0.46) | GAAATMTSHRRXFP1CHRNA7 | |
| SCHEMBL9469137 | 0.76 | LSS (0.52) | GAAATMLSSTSHRRXFP1 | |
| SCHEMBL9469800 | 0.75 | CHRM2 (0.45) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9469096 | 0.75 | CHRM2 (0.45) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9469146 | 0.75 | CHRM2 (0.45) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9469630 | 0.75 | CHRM2 (0.45) | CHRNA7CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |