Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | DHODH | Q02127 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838484 | 0.87 | RAB9A (0.54) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL15038511 | 0.80 | RAB9A (0.51) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL9469341 | 0.78 | RAB9A (0.43) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL9469395 | 0.76 | DHODH (1.00) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL15215720 | 0.75 | RAB9A (0.49) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL15204805 | 0.75 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL29999657 | 0.75 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL16616388 | 0.74 | RAB9A (0.76) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL29898323 | 0.74 | RAB9A (0.76) | RAB9ASMN1; SMN2DHODHMEN1KMT2A | |
| SCHEMBL28824933 | 0.74 | RAB9A (0.76) | RAB9ASMN1; SMN2DHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182289-A | Pyrrolo 2,3-b!Pyridin-2-one Derivatives | SCHERING CORPORATION (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0419561-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1991-04-03 | — | — | EP | disclosed |
| WO-1989012637-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1989-12-28 | — | — | WO | disclosed |
| EP-0347698-A1 | Heterobicyclic compounds having antiinflammatory activity | SCHERING CORPORATION (US) | 1989-12-27 | — | — | EP | disclosed |