Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21248269 | 0.98 | TAAR1 (0.74) | TAAR1POLBALDH1A1TDP1CYP1A2 | |
| SCHEMBL14154 | 0.94 | TAAR1 (0.74) | TAAR1POLBALDH1A1TDP1CYP1A2 | |
| SCHEMBL10110932 | 0.92 | TAAR1 (0.71) | TAAR1POLBALDH1A1TDP1CYP1A2 | |
| SCHEMBL1869457 | 0.87 | TAAR1 (1.00) | TAAR1POLBALDH1A1TDP1CYP1A2 | |
| SCHEMBL3903774 | 0.83 | TAAR1 (0.53) | TAAR1ALDH1A1TDP1CYP1A2CYP2A6 | |
| SCHEMBL9491792 | 0.82 | TAAR1 (0.74) | TAAR1POLBALDH1A1TDP1CYP1A2 | |
| SCHEMBL630179 | 0.81 | TAAR1 (0.61) | TAAR1POLBALDH1A1TDP1CYP3A4 | |
| SCHEMBL12525643 | 0.80 | TAAR1 (0.50) | TAAR1ALDH1A1TDP1CYP1A2HTR2A | |
| SCHEMBL3314163 | 0.80 | TAAR1 (0.60) | TAAR1POLBALDH1A1TDP1TACR1 | |
| SCHEMBL38650825 | 0.79 | TAAR1 (0.59) | TAAR1POLBALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150252056-A1 | BICYCLIC OXA-LACTAM KINASE INHIBITORS | ALEXION PHARMACEUTICALS, INC. | 2015-09-10 | — | — | US | disclosed |
| US-20140113931-A1 | SUBSTITUTED PICOLINAMIDE KINASE INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-04-24 | — | — | US | disclosed |
| US-5225455-A | Hardeners and Bisphenol F resins | STONHARD, INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0438498-A4 | BISPHENOL FORMALDEHYDE EPOXY-BASED FLOORING AND COATING MATERIALS | — | 1992-05-13 | — | — | EP | disclosed |
| EP-0438498-A1 | BISPHENOL FORMALDEHYDE EPOXY-BASED FLOORING AND COATING MATERIALS | STONHARD INC (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4980400-A | IMPACT, CHEMICAL, AND WEAR RESISTANCE | STONHARD (US) | 1990-12-25 | — | — | US | disclosed |
| WO-1990004000-A1 | BISPHENOL FORMALDEHYDE EPOXY-BASED FLOORING AND COATING MATERIALS | STONHARD, INC. (US) | 1990-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252056-A1 | BICYCLIC OXA-LACTAM KINASE INHIBITORS | SYK, BTK, JAK2 | TAAR1 4613/4885POLB 1893/4885ALDH1A1 4320/4885 |
| US-20140113931-A1 | SUBSTITUTED PICOLINAMIDE KINASE INHIBITORS | SYK, LCK, BTK | TAAR1 3103/4885POLB 2837/4885ALDH1A1 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.