Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469825 | 0.75 | CHRNA7 (0.41) | MAPTALDH1A1KMT2AMEN1APOBEC3G | |
| SCHEMBL875286 | 0.74 | MAPT (0.57) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL9469499 | 0.71 | DDB1 (0.43) | MAPTKMT2AMEN1NPSR1CHRNA7 | |
| SCHEMBL8328341 | 0.71 | MAPT (0.56) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL5262117 | 0.71 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL3217634 | 0.71 | CHRNA7 (0.50) | CHRNA7 | |
| SCHEMBL3217644 | 0.71 | CHRNA7 (0.50) | CHRNA7 | |
| SCHEMBL6759187 | 0.70 | MAPT (0.65) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL31315669 | 0.70 | MAPT (0.65) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL9469015 | 0.69 | MEN1 (0.47) | ALDH1A1KMT2AMEN1TDP1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |