Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262117 | 0.80 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL31315669 | 0.78 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL6759187 | 0.78 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL875286 | 0.76 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL8028472 | 0.76 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL9469352 | 0.71 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL397345 | 0.68 | PDE7A (0.56) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL224666 | 0.67 | PDE7A (0.60) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL875772 | 0.67 | PDE7A (0.78) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL31272173 | 0.67 | PDE7A (0.78) | MAPTALDH1A1MEN1KMT2AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |