SCHEMBL9469370

SCHEMBL9469370

CCC(C)(C)c1ccc(OCCCC[N]C(N)=O)c(C(C)(C)CC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.55
NPSR1 Q6W5P4 5/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPT P10636 4/20 0.54
HTT P42858 3/20 0.54
UBE2N P61088 2/20 0.54
GLA P06280 1/20 0.54
MITF O75030 1/20 0.54
RAD52 P43351 2/20 0.49
STAT3 P40763 1/20 0.49
RCE1 Q9Y256 1/20 0.49
APAF1 O14727 1/20 0.49
HSP90AA1 P07900 1/20 0.49
RAB9A P51151 1/20 0.49
NOD2 Q9HC29 1/20 0.49
RRM1 P23921 1/20 0.42
TLR4 O00206 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9171751 0.96 MAPK1 (0.56) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL4477633 0.84 MAPK1 (0.61) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL9353082 0.80 MAPK1 (0.56) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL1638711 0.79 MAPK1 (0.63) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL6536664 0.79 MAPK1 (0.63) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL8593377 0.79 MAPK1 (0.66) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL1285803 0.79 MAPK1 (0.61) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL12548316 0.79 MAPK1 (0.61) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL7913061 0.78 MAPK1 (0.62) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL1061587 0.78 MAPK1 (0.71) MAPK1NPSR1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5229248-A Hydrazine compound or derivative and amines or quaternary ammonium compounds, high contrast KONICA CORPORATION (JP) 1993-07-20 US disclosed
EP-0473342-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1992-03-04 EP disclosed