Medronic Acid

Medronic Acid

SCHEMBL9469376

C1CN1.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.67
MMP2 P08253 1/20 0.67
THRB P10828 1/20 0.67
MAPK1 P28482 1/20 0.67
HSD17B10 Q99714 1/20 0.67
OTC P00480 1/20 0.41
ANPEP P15144 2/20 0.36
ERAP2 Q6P179 2/20 0.36
TYMS P04818 1/20 0.35
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medronic Acid SCHEMBL9222563 0.97 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL9485739 0.97 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL9485093 0.97 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL9810806 0.97 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL10954777 0.97 KDM4E (0.62) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL402438 0.87 KDM4E (0.50) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL8057993 0.84 KDM4E (0.50) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL8350837 0.82 KDM4E (1.00) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL66716 0.82
Medronic Acid SCHEMBL6365875 0.78 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232680-A Chelation of metal ions with chelating agent and adsorption of organic impurities onto a polymer to remove them from distilled hydrogen peroxide PEROXID-CHEMIE GMBH (DE) 1993-08-03 US disclosed
US-4525291-A STABILIZERS FOR HYDROGEN PEROXIDE COMPONENT, LOWER ALCOHOL WITH A POLYHYDROXY CARBOXYLATE AND A HYDROXY OR AMINO INTEROX CHEMICALS LIMITED (GB) 1985-06-25 US disclosed
EP-0037184-A2 Liquid detergent compositions, their manufacture and their use in washing processes Interox Chemicals Limited (GB) 1981-10-07 EP disclosed
US-4269725-A COMPRISING A SURFACTANT AND A MIXTURES OF ZEOLITES; RATIOS OF SODIUM, ALUMINUM, AND SILICON OXIDES; SYNERGISTIC LAPORTE INDUSTRIES LIMITED (GB) 1981-05-26 US disclosed