Medronic Acid

Medronic Acid

SCHEMBL8057993

C1COCCN1.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GAA P10253 1/20 0.50
CYP2C9 P11712 1/20 0.50
MMP2 P08253 1/20 0.48
THRB P10828 1/20 0.48
MAPK1 P28482 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ANPEP P15144 2/20 0.34
OTC P00480 1/20 0.32
MMP1 P03956 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31
ERAP2 Q6P179 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL3142248 0.88 KDM4E (0.48) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL29071034 0.85 MEN1 (0.61) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL29377463 0.85 MEN1 (0.61) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL20580623 0.85 MEN1 (0.61) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL7727917 0.85 MEN1 (0.61) KDM4EMEN1KMT2AGAACYP2C9
Morpholine SCHEMBL11120537 0.85 MEN1 (0.61) KDM4EMEN1KMT2AGAACYP2C9
Medronic Acid SCHEMBL9469376 0.84 KDM4E (0.67) KDM4EMEN1KMT2AMMP2THRB
Morpholine SCHEMBL11664356 0.84 MEN1 (0.48) KDM4EMEN1KMT2AGAACYP2C9
Medronic Acid SCHEMBL9485739 0.82 KDM4E (0.62) KDM4EMEN1KMT2AMMP2THRB
Medronic Acid SCHEMBL9810806 0.82 KDM4E (0.62) KDM4EMEN1KMT2AMMP2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1255316-C Chemical composition and method AKZO NOBEL NV (NL) 2006-05-10 CN claimed
CN-1355767-A Chemical compositions and methods AKZO NOBEL NV (NL) 2002-06-26 CN claimed
CN-101617000-A Surface treatment method for nanoparticles CT ANGEWANDTE NANOTECH CAN 2009-12-30 CN disclosed
CN-1255316-C Chemical composition and method AKZO NOBEL NV (NL) 2006-05-10 CN disclosed
CN-1355767-A Chemical compositions and methods AKZO NOBEL NV (NL) 2002-06-26 CN disclosed
US-6083403-A METAL SURFACES NALCO CHEMICAL COMPANY (US) 2000-07-04 US disclosed