Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469432 | 1.00 | PTGIR (0.50) | PTGIRPPARGGPR132PTGDR2LTB4R2 | |
| SCHEMBL9469434 | 1.00 | PTGIR (0.50) | PTGIRPPARGGPR132PTGDR2LTB4R2 | |
| SCHEMBL9521127 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9469174 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9469165 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9469170 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9469166 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9521115 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9469168 | 0.91 | PPARG (0.53) | PPARGGPR132LTB4R2ALOX5MAPT | |
| SCHEMBL9518443 | 0.90 | PPARG (0.55) | PPARGGPR132LTB4R2FPR2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416069-B1 | NEW LEUCOTRIENE B 4 DERIVATIVES, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | claimed |
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |