Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469170 | 1.00 | PPARG (0.53) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9469168 | 1.00 | PPARG (0.53) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9469165 | 1.00 | PPARG (0.53) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9469174 | 1.00 | PPARG (0.53) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9521127 | 1.00 | PPARG (0.53) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9469166 | 1.00 | PPARG (0.53) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9518451 | 0.97 | PPARG (0.55) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9518443 | 0.97 | PPARG (0.55) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9469433 | 0.91 | PTGIR (0.50) | PPARGGPR132LTB4R2FPR2NFKB1 | |
| SCHEMBL9469434 | 0.91 | PTGIR (0.50) | PPARGGPR132LTB4R2FPR2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416069-B1 | NEW LEUCOTRIENE B 4 DERIVATIVES, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | claimed |