Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 8/20 | 0.50 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937792 | 1.00 | POLB (0.63) | POLBLTA4HMAN1B1KMT2ACXCR4 | |
| SCHEMBL1162536 | 0.95 | POLB (0.56) | POLBLTA4HMAN1B1KMT2ACXCR4 | |
| SCHEMBL1162602 | 0.95 | POLB (0.56) | POLBLTA4HMAN1B1KMT2ACXCR4 | |
| SCHEMBL8854588 | 0.95 | POLB (0.56) | POLBLTA4HMAN1B1KMT2ACXCR4 | |
| SCHEMBL1750429 | 0.86 | POLB (0.46) | POLBLTA4HMAN1B1KMT2A | |
| SCHEMBL13278472 | 0.86 | POLB (0.61) | POLBLTA4HKMT2ASIGMAR1 | |
| SCHEMBL28806486 | 0.84 | POLB (0.44) | POLB | |
| SCHEMBL23022845 | 0.84 | POLB (0.59) | POLBLTA4HKMT2ASIGMAR1 | |
| SCHEMBL27928440 | 0.83 | CYP2D6 (0.53) | POLBKMT2ACXCR4 | |
| SCHEMBL20056668 | 0.81 | POLB (0.54) | POLBLTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189046-A | Antiinflammatory agents, anticonvulsants | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| WO-1992003415-A1 | PROTEIN KINASE C MODULATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |